6DUC
Crystal structure of mutant beta-K167T tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid (1D0) at the beta-site
6DUC の概要
エントリーDOI | 10.2210/pdb6duc/pdb |
関連するPDBエントリー | 4HPJ |
分子名称 | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (10 entities in total) |
機能のキーワード | f9f, 1d0, cesium ion, mutant beta-k167t, lyase, lyase inhibitor, 2-aminophenol quinonoid, salmonella typhimurium, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
由来する生物種 | Salmonella typhimurium (Salmonella enterica subsp. enterica serovar Typhimurium) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 73918.97 |
構造登録者 | |
主引用文献 | Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. Tryptophan synthase Q114A mutant in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate (P1T) at the beta site, and cesium ion at the metal coordination site. To be Published, |
実験手法 | X-RAY DIFFRACTION (1.791 Å) |
構造検証レポート
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