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6DRG

NMR solution structure of wild type hFABP1 with GW7647

Summary for 6DRG
Entry DOI10.2210/pdb6drg/pdb
NMR InformationBMRB: 30478
DescriptorFatty acid-binding protein, liver, 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid (2 entities in total)
Functional Keywordshlfabp, gw7647, lipid binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight15728.21
Authors
Scanlon, M.J.,Mohanty, B.,Doak, B.C.,Patil, R. (deposition date: 2018-06-11, release date: 2018-12-26, Last modification date: 2020-01-01)
Primary citationPatil, R.,Mohanty, B.,Liu, B.,Chandrashekaran, I.R.,Headey, S.J.,Williams, M.L.,Clements, C.S.,Ilyichova, O.,Doak, B.C.,Genissel, P.,Weaver, R.J.,Vuillard, L.,Halls, M.L.,Porter, C.J.H.,Scanlon, M.J.
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.
J. Biol. Chem., 294:3720-3734, 2019
Cited by
PubMed: 30598509
DOI: 10.1074/jbc.RA118.006848
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

數據於2024-03-27公開中

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