6DRG

NMR solution structure of wild type hFABP1 with GW7647

6DRG の概要

• エントリーDOI: 10.2210/pdb6drg/pdb
• NMR情報: BMRB: 30478
• 分子名称: Fatty acid-binding protein, liver, 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid (2 entities in total)
• 機能のキーワード: hlfabp, gw7647, lipid binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15728.21

構造登録者

Scanlon, M.J.,Mohanty, B.,Doak, B.C.,Patil, R. (登録日: 2018-06-11, 公開日: 2018-12-26, 最終更新日: 2020-01-01)

• 主引用文献: Patil, R.,Mohanty, B.,Liu, B.,Chandrashekaran, I.R.,Headey, S.J.,Williams, M.L.,Clements, C.S.,Ilyichova, O.,Doak, B.C.,Genissel, P.,Weaver, R.J.,Vuillard, L.,Halls, M.L.,Porter, C.J.H.,Scanlon, M.J.; A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.; J. Biol. Chem., 294:3720-3734, 2019; PubMed: 30598509; DOI: 10.1074/jbc.RA118.006848

実験手法

SOLUTION NMR