6DNT

UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with UDP-N-acetylmuramic acid

Summary for 6DNT

• Entry DOI: 10.2210/pdb6dnt/pdb
• Descriptor: NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, ... (6 entities in total)
• Functional Keywords: udp-n-acetylglucosamine, wbpp, 4-epimerase, udp-n-acetylmuramic acid, sugar binding protein
• Biological source: Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1) (Methanobacterium ruminantium)
• Total number of polymer chains: 1
• Total formula weight: 40292.08

Authors

Carbone, V.,Schofield, L.R.,Sang, C.,Sutherland-Smith, A.J.,Ronimus, R.S. (deposition date: 2018-06-07, release date: 2018-10-03, Last modification date: 2023-10-11)

• Primary citation: Carbone, V.,Schofield, L.R.,Sang, C.,Sutherland-Smith, A.J.,Ronimus, R.S.; Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid.; Proteins, 86:1306-1312, 2018; PubMed: 30242905; DOI: 10.1002/prot.25606

Experimental method

X-RAY DIFFRACTION (1.66 Å)