6DMY

Cryo-EM structure of human Ptch1 and ShhN complex

Summary for 6DMY

• Entry DOI: 10.2210/pdb6dmy/pdb
• EMDB information: 7968
• Descriptor: Protein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: receptor, rnd family, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 172878.59

Authors

Yan, N.,Gong, X.,Qian, H.W. (deposition date: 2018-06-05, release date: 2018-07-11, Last modification date: 2020-07-29)

• Primary citation: Gong, X.,Qian, H.,Cao, P.,Zhao, X.,Zhou, Q.,Lei, J.,Yan, N.; Structural basis for the recognition of Sonic Hedgehog by human Patched1.; Science, 361:-, 2018; PubMed: 29954986; DOI: 10.1126/science.aas8935

Experimental method

ELECTRON MICROSCOPY (3.6 Å)