6DH9

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602

Summary for 6DH9

• Entry DOI: 10.2210/pdb6dh9/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, (5S)-5-({4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, nonanoic acid, ... (4 entities in total)
• Functional Keywords: nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 62523.69

Authors

Shang, J.,Kojetin, D.J. (deposition date: 2018-05-18, release date: 2019-05-22, Last modification date: 2023-10-11)

• Primary citation: Shang, J.,Kojetin, D.J.; Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)