6DG7

Full-length 5-HT3A receptor in a serotonin-bound conformation- State 1

6DG7 の概要

• エントリーDOI: 10.2210/pdb6dg7/pdb
• EMDBエントリー: 7882 7883
• 分子名称: 5-hydroxytryptamine receptor 3A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: membrane protein
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 270676.10

構造登録者

Basak, S.,Chakrapani, S. (登録日: 2018-05-17, 公開日: 2018-11-07, 最終更新日: 2020-07-29)

• 主引用文献: Basak, S.,Gicheru, Y.,Rao, S.,Sansom, M.S.P.,Chakrapani, S.; Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor.; Nature, 563:270-274, 2018; PubMed: 30401837; DOI: 10.1038/s41586-018-0660-7

実験手法

ELECTRON MICROSCOPY (3.32 Å)