6DFE

The structure of a ternary complex of E. coli WaaC

6DFE の概要

• エントリーDOI: 10.2210/pdb6dfe/pdb
• 分子名称: ADP-heptose--LPS heptosyltransferase, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R)-1-{(2S,3S,4R,5S,6R)-6-[(1S)-1,2-dihydroxyethyl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}propan-2-yl hydrogen (R)-phosphate (non-preferred name), ... (4 entities in total)
• 機能のキーワード: llipopolysaccharide heptosyltransferase, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75697.26

構造登録者

Worrall, L.J.,Blaukopf, M.,Withers, S.G.,Strynadka, N.C.J. (登録日: 2018-05-14, 公開日: 2018-09-05, 最終更新日: 2023-10-11)

• 主引用文献: Blaukopf, M.,Worrall, L.,Kosma, P.,Strynadka, N.C.J.,Withers, S.G.; Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex.; Structure, 26:1399-1407.e5, 2018; PubMed: 30122450; DOI: 10.1016/j.str.2018.07.001

実験手法

X-RAY DIFFRACTION (2.31 Å)