6DF2

Improved anti-phosphotyrosine antibody 4G10-S5-4D5 Fab complexed with phosphotyrosine peptide

6DF2 の概要

• エントリーDOI: 10.2210/pdb6df2/pdb
• 分子名称: Anti-phosphotyrosine antibody c310-4D5 heavy chain, Anti-phosphotyrosine antibody c310-4D5 light chain, LEU-PTR-LEU, ... (4 entities in total)
• 機能のキーワード: antibody, recombination, immune system
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 111292.31

構造登録者

Mou, K.,Leung, K.,Wells, J.A. (登録日: 2018-05-13, 公開日: 2018-11-28, 最終更新日: 2023-11-15)

• 主引用文献: Mou, Y.,Zhou, X.X.,Leung, K.,Martinko, A.J.,Yu, J.Y.,Chen, W.,Wells, J.A.; Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.; J. Am. Chem. Soc., 140:16615-16624, 2018; PubMed: 30398859; DOI: 10.1021/jacs.8b08402

実験手法

X-RAY DIFFRACTION (2.6 Å)