6DEE

Crystal structure of the C-terminus of Homo sapiens SPIN90 (SH3-protein interacting with Nck), residues 306-722

6DEE の概要

• エントリーDOI: 10.2210/pdb6dee/pdb
• 分子名称: NCK-interacting protein with SH3 domain (1 entity in total)
• 機能のキーワード: partially active form, n-terminally truncated spin90, 6 and half armadillo repeats, part of middle segment, activates arp2-3 complex, not full activity, endocytosis
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46973.59

構造登録者

Nolen, B.J.,Luan, Q. (登録日: 2018-05-11, 公開日: 2018-10-24, 最終更新日: 2023-10-11)

• 主引用文献: Luan, Q.,Liu, S.L.,Helgeson, L.A.,Nolen, B.J.; Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex.; EMBO J., 37:-, 2018; PubMed: 30322896; DOI: 10.15252/embj.2018100005

実験手法

X-RAY DIFFRACTION (3.04 Å)