6DDR

Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody

6DDR の概要

• エントリーDOI: 10.2210/pdb6ddr/pdb
• 分子名称: Anti-MICA Fab fragment light chain clone 13A9, Anti-MICA Fab fragment heavy chain clone 13A9, MHC class I polypeptide-related sequence A, ... (7 entities in total)
• 機能のキーワード: fab fragment-antigen complex, immunoglobulin domain, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 58476.07

構造登録者

Matsumoto, M.L. (登録日: 2018-05-10, 公開日: 2018-10-24, 最終更新日: 2023-10-11)

• 主引用文献: Lombana, T.N.,Matsumoto, M.L.,Berkley, A.M.,Toy, E.,Cook, R.,Gan, Y.,Du, C.,Schnier, P.,Sandoval, W.,Ye, Z.,Schartner, J.M.,Kim, J.,Spiess, C.; High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.; MAbs, 11:75-93, 2019; PubMed: 30307368; DOI: 10.1080/19420862.2018.1532767

実験手法

X-RAY DIFFRACTION (1.9 Å)