6DDM
Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
Summary for 6DDM
Entry DOI | 10.2210/pdb6ddm/pdb |
Descriptor | Anti-MICA Fab fragment light chain clone 1D5, MHC class I polypeptide-related sequence A, Anti-MICA Fab fragment heavy chain clone 1D5, ... (4 entities in total) |
Functional Keywords | fab fragment-antigen complex, immunoglobulin domain, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 57239.75 |
Authors | Matsumoto, M.L. (deposition date: 2018-05-10, release date: 2018-10-24, Last modification date: 2023-10-11) |
Primary citation | Lombana, T.N.,Matsumoto, M.L.,Berkley, A.M.,Toy, E.,Cook, R.,Gan, Y.,Du, C.,Schnier, P.,Sandoval, W.,Ye, Z.,Schartner, J.M.,Kim, J.,Spiess, C. High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11:75-93, 2019 Cited by PubMed: 30307368DOI: 10.1080/19420862.2018.1532767 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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