6DAX

X-ray crystal structure of VioC bound to Fe(II), L-homoarginine, and 2-oxoglutarate

6DAX の概要

• エントリーDOI: 10.2210/pdb6dax/pdb
• 分子名称: Alpha-ketoglutarate-dependent L-arginine hydroxylase, 2-OXOGLUTARIC ACID, L-HOMOARGININE, ... (5 entities in total)
• 機能のキーワード: desaturase, hydroxylase, oxygenase, metalloenzyme, desaturation, hydroxylation, viomycin, oxidoreductase
• 由来する生物種: Streptomyces vinaceus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37883.24

構造登録者

Dunham, N.P.,Mitchell, A.J.,Boal, A.K. (登録日: 2018-05-02, 公開日: 2018-05-16, 最終更新日: 2024-03-13)

• 主引用文献: Dunham, N.P.,Chang, W.C.,Mitchell, A.J.,Martinie, R.J.,Zhang, B.,Bergman, J.A.,Rajakovich, L.J.,Wang, B.,Silakov, A.,Krebs, C.,Boal, A.K.,Bollinger, J.M.; Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance.; J. Am. Chem. Soc., 140:7116-7126, 2018; PubMed: 29708749; DOI: 10.1021/jacs.8b01933

実験手法

X-RAY DIFFRACTION (1.7 Å)