6D86

Structure of the Bovine p85a BH domain

Summary for 6D86

• Entry DOI: 10.2210/pdb6d86/pdb
• Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION (3 entities in total)
• Functional Keywords: gap protein, signaling protein
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 2
• Total formula weight: 44010.55

Authors

Moore, S.A.,Marshall, J.D.,Anderson, D.H. (deposition date: 2018-04-25, release date: 2018-05-23, Last modification date: 2020-01-08)

• Primary citation: Mellor, P.,Marshall, J.D.S.,Ruan, X.,Whitecross, D.E.,Ross, R.L.,Knowles, M.A.,Moore, S.A.,Anderson, D.H.; Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.; Sci Rep, 8:7108-7108, 2018; PubMed: 29740032; DOI: 10.1038/s41598-018-25487-5

Experimental method

X-RAY DIFFRACTION (2.301 Å)