6D3Q

Crystal structure of Escherichia coli enolase complexed with a natural inhibitor SF2312.

Summary for 6D3Q

• Entry DOI: 10.2210/pdb6d3q/pdb
• Descriptor: Enolase, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: enolase, complex, natural inhibitor, sf2312, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 6
• Total formula weight: 281821.25

Authors

Erlandsen, H.,Krucinska, J.,Hazeen, A.,Wright, D. (deposition date: 2018-04-16, release date: 2019-11-27, Last modification date: 2023-10-04)

• Primary citation: Krucinska, J.,Lombardo, M.N.,Erlandsen, H.,Hazeen, A.,Duay, S.S.,Pattis, J.G.,Robinson, V.L.,May, E.R.,Wright, D.L.; Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.; Sci Rep, 9:17106-17106, 2019; PubMed: 31745118; DOI: 10.1038/s41598-019-53301-3

Experimental method

X-RAY DIFFRACTION (2.24 Å)