6D2Z
Structure of human Usb1 with uridine-adenosine, inactive H208Q mutant
Summary for 6D2Z
Entry DOI | 10.2210/pdb6d2z/pdb |
Descriptor | U6 snRNA phosphodiesterase, 5'-R(UP*A)-3'), CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | exonuclease, u6 snrna, 2h phosphodiesterase superfamily, hydrolase, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 22802.35 |
Authors | Nomura, Y.,Montemayor, E.J.,Butcher, S.E. (deposition date: 2018-04-14, release date: 2018-09-05, Last modification date: 2023-10-04) |
Primary citation | Nomura, Y.,Roston, D.,Montemayor, E.J.,Cui, Q.,Butcher, S.E. Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1. Nucleic Acids Res., 46:11488-11501, 2018 Cited by PubMed: 30215753DOI: 10.1093/nar/gky812 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.18 Å) |
Structure validation
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