6D0V

Tryptophan synthase Q114A mutant in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site

Summary for 6D0V

• Entry DOI: 10.2210/pdb6d0v/pdb
• Descriptor: Tryptophan synthase alpha chain, DI(HYDROXYETHYL)ETHER, Tryptophan synthase beta chain, ... (11 entities in total)
• Functional Keywords: f9f ligand, cesium ion, mutant beta-q114a, lyase, p1t ligand, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2; More
• Total number of polymer chains: 2
• Total formula weight: 74711.83

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2018-04-11, release date: 2019-04-17, Last modification date: 2023-10-04)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L.; Tryptophan synthase Q114A mutant in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)