6CXV
Structure of the S167H mutant of human indoleamine 2,3 dioxygenase in complex with tryptophan and cyanide
Summary for 6CXV
Entry DOI | 10.2210/pdb6cxv/pdb |
Descriptor | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, CYANIDE ION, ... (6 entities in total) |
Functional Keywords | heme, dioxygenase, tryptophan, ido, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 97701.83 |
Authors | Lewis-Ballester, A.,Yeh, S.-R.,Karkashon, S.,Batabyal, D.,Poulos, T.L. (deposition date: 2018-04-04, release date: 2018-06-27, Last modification date: 2023-10-04) |
Primary citation | Lewis-Ballester, A.,Karkashon, S.,Batabyal, D.,Poulos, T.L.,Yeh, S.R. Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1. J. Am. Chem. Soc., 140:8518-8525, 2018 Cited by PubMed: 29897749DOI: 10.1021/jacs.8b03691 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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