6CWZ
Crystal structure of apo SUMO E1
Summary for 6CWZ
Entry DOI | 10.2210/pdb6cwz/pdb |
Related | 6CWY |
Descriptor | SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ZINC ION (3 entities in total) |
Functional Keywords | rossmann-like fold, ubiquitin-like fold, ubiquitin activating enzyme, activity, atp binding, ligase activity, atp/mg binding, ubiquitin e2, ligase, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 112051.09 |
Authors | Lv, Z.,Yuan, L.,Atkison, J.H.,Williams, K.M.,Olsen, S.K. (deposition date: 2018-04-01, release date: 2019-01-16, Last modification date: 2023-10-04) |
Primary citation | Lv, Z.,Yuan, L.,Atkison, J.H.,Williams, K.M.,Vega, R.,Sessions, E.H.,Divlianska, D.B.,Davies, C.,Chen, Y.,Olsen, S.K. Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9:5145-5145, 2018 Cited by PubMed: 30514846DOI: 10.1038/s41467-018-07015-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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