6CVZ

Crystal structure of the WD40-repeat of RFWD3

Summary for 6CVZ

• Entry DOI: 10.2210/pdb6cvz/pdb
• Descriptor: E3 ubiquitin-protein ligase RFWD3, MAGNESIUM ION (3 entities in total)
• Functional Keywords: wd40-repeat, rfwd3, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 116469.82

Authors

DONG, A.,LOPPNAU, P.,SEITOVA, A.,HUTCHINSON, A.,TEMPEL, W.,WEI, Y.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,BROWN, P.J.,TONG, Y.,Structural Genomics Consortium (SGC) (deposition date: 2018-03-29, release date: 2018-06-27, Last modification date: 2024-10-09)

Primary citation

Lepore, R.,Kryshtafovych, A.,Alahuhta, M.,Veraszto, H.A.,Bomble, Y.J.,Bufton, J.C.,Bullock, A.N.,Caba, C.,Cao, H.,Davies, O.R.,Desfosses, A.,Dunne, M.,Fidelis, K.,Goulding, C.W.,Gurusaran, M.,Gutsche, I.,Harding, C.J.,Hartmann, M.D.,Hayes, C.S.,Joachimiak, A.,Leiman, P.G.,Loppnau, P.,Lovering, A.L.,Lunin, V.V.,Michalska, K.,Mir-Sanchis, I.,Mitra, A.K.,Moult, J.,Phillips Jr., G.N.,Pinkas, D.M.,Rice, P.A.,Tong, Y.,Topf, M.,Walton, J.D.,Schwede, T.
Target highlights in CASP13: Experimental target structures through the eyes of their authors.
Proteins, 87:1037-1057, 2019

PubMed Abstract: The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

PubMed: 31442339
DOI: 10.1002/prot.25805

Experimental method

X-RAY DIFFRACTION (1.8 Å)