6CSW

Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor

6CSW の概要

• エントリーDOI: 10.2210/pdb6csw/pdb
• 分子名称: Serine/threonine-protein kinase VRK1, SULFATE ION, ACETATE ION, ... (8 entities in total)
• 機能のキーワード: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 168611.01

構造登録者

dos Reis, C.V.,de Souza, G.P.,Counago, R.M.,Chiodi, C.G.,Azevedo, A.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (登録日: 2018-03-21, 公開日: 2018-04-04, 最終更新日: 2023-10-04)

• 主引用文献: dos Reis, C.V.,de Souza, G.P.,Counago, R.M.,Azevedo, H.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC); Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.25 Å)