6CR1

adalimumab EFab

Summary for 6CR1

• Entry DOI: 10.2210/pdb6cr1/pdb
• Descriptor: Light chain of adalimumab EFab (VL-IgE CH2), Heavy chain of adalimumab EFab (VH-IgE CH2), DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: efab, ige, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48518.82

Authors

Arndt, J.W. (deposition date: 2018-03-16, release date: 2018-09-26, Last modification date: 2023-10-04)

• Primary citation: Cooke, H.A.,Arndt, J.,Quan, C.,Shapiro, R.I.,Wen, D.,Foley, S.,Vecchi, M.M.,Preyer, M.; EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies.; MAbs, 10:1248-1259, 2018; PubMed: 30215570; DOI: 10.1080/19420862.2018.1519631

Experimental method

X-RAY DIFFRACTION (1.521 Å)