6CPE
Structure of apo, dephosphorylated Aurora A (122-403) in an active conformation
Summary for 6CPE
| Entry DOI | 10.2210/pdb6cpe/pdb |
| Descriptor | Aurora kinase A, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE (3 entities in total) |
| Functional Keywords | protein kinase, dfg-loop, transferase, cell cycle |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 33152.98 |
| Authors | Otten, R.,Kutter, S.,Buosi, V.,Padua, R.A.P.,Kern, D. (deposition date: 2018-03-13, release date: 2018-06-27, Last modification date: 2023-10-04) |
| Primary citation | Pitsawong, W.,Buosi, V.,Otten, R.,Agafonov, R.V.,Zorba, A.,Kern, N.,Kutter, S.,Kern, G.,Padua, R.A.,Meniche, X.,Kern, D. Dynamics of human protein kinase Aurora A linked to drug selectivity. Elife, 7:-, 2018 Cited by PubMed: 29901437DOI: 10.7554/eLife.36656 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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