6CNX
Crystal Structure of the Human vaccinia-related kinase 1 (VRK1) bound to an N-propynyl-N-isopentyl-dihydropteridin inhibitor
6CNX の概要
エントリーDOI | 10.2210/pdb6cnx/pdb |
分子名称 | Serine/threonine-protein kinase VRK1, (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, SULFATE ION, ... (7 entities in total) |
機能のキーワード | transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 167517.21 |
構造登録者 | Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Azevedo, A.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (登録日: 2018-03-09, 公開日: 2018-04-04, 最終更新日: 2023-10-04) |
主引用文献 | Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Gama, F.,Azevedo, H.,Guimaraes, C.,Mascarello, A.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) Crystal Structure of the Human Vaccinia-Related Kinase 1 (VRK1) bound to a N-propynyl-N-isopentil-dihydropteridine inhibitor To Be Published, |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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