6CEY
Aminoglycoside Phosphotransferase (2'')-Ia in complex with GMPPNP, Magnesium, and Lividomycin moieties
Summary for 6CEY
Entry DOI | 10.2210/pdb6cey/pdb |
Descriptor | Bifunctional AAC/APH, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | kinase, antibiotic, aminoglycoside, resistance, transferase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 146968.45 |
Authors | Caldwell, S.J.,Berghuis, A.M. (deposition date: 2018-02-13, release date: 2018-04-11, Last modification date: 2023-10-04) |
Primary citation | Caldwell, S.J.,Berghuis, A.M. Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia. Antimicrob. Agents Chemother., 62:-, 2018 Cited by PubMed: 29661878DOI: 10.1128/AAC.00202-18 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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