6CEY

Aminoglycoside Phosphotransferase (2'')-Ia in complex with GMPPNP, Magnesium, and Lividomycin moieties

Summary for 6CEY

• Entry DOI: 10.2210/pdb6cey/pdb
• Descriptor: Bifunctional AAC/APH, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: kinase, antibiotic, aminoglycoside, resistance, transferase, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 4
• Total formula weight: 146968.45

Authors

Caldwell, S.J.,Berghuis, A.M. (deposition date: 2018-02-13, release date: 2018-04-11, Last modification date: 2023-10-04)

• Primary citation: Caldwell, S.J.,Berghuis, A.M.; Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.; Antimicrob. Agents Chemother., 62:-, 2018; PubMed: 29661878; DOI: 10.1128/AAC.00202-18

Experimental method