6CDZ

E. coli thymidylate synthase mutant I264Am

Summary for 6CDZ

• Entry DOI: 10.2210/pdb6cdz/pdb
• Descriptor: Thymidylate synthase, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... (5 entities in total)
• Functional Keywords: transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 62466.34

Authors

Finer-moore, J.S.,Lee, T.T.,Stroud, R.M. (deposition date: 2018-02-09, release date: 2018-05-16, Last modification date: 2023-10-04)

• Primary citation: Finer-Moore, J.S.,Lee, T.T.,Stroud, R.M.; A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer.; Biochemistry, 57:2786-2795, 2018; PubMed: 29717875; DOI: 10.1021/acs.biochem.8b00176

Experimental method

X-RAY DIFFRACTION (2.4 Å)