6C1U

MBD2 in complex with a deoxy-oligonucleotide

6C1U の概要

• エントリーDOI: 10.2210/pdb6c1u/pdb
• 分子名称: Methyl-CpG-binding domain protein 2, 12-mer DNA, UNKNOWN ATOM OR ION, ... (5 entities in total)
• 機能のキーワード: mbd, dna-binding, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus : Q9UBB5
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 49848.28

構造登録者

Lei, M.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2018-01-05, 公開日: 2018-02-14, 最終更新日: 2024-04-03)

• 主引用文献: Liu, K.,Xu, C.,Lei, M.,Yang, A.,Loppnau, P.,Hughes, T.R.,Min, J.; Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.; J. Biol. Chem., 293:7344-7354, 2018; PubMed: 29567833; DOI: 10.1074/jbc.RA118.001785

実験手法

X-RAY DIFFRACTION (2.3 Å)