6BXN

Crystal structure of Candidatus Methanoperedens nitroreducens Dph2 with 4Fe-4S cluster and SAM

6BXN の概要

• エントリーDOI: 10.2210/pdb6bxn/pdb
• 分子名称: Diphthamide biosynthesis enzyme Dph2, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• 機能のキーワード: diphthamide biosynthesis, radical sam enzyme, biosynthetic protein
• 由来する生物種: Candidatus Methanoperedens nitroreducens
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74418.83

構造登録者

Fenwick, M.K.,Torelli, A.T.,Zhang, Y.,Dong, M.,Kathiresan, V.,Carantoa, J.D.,Dzikovski, B.,Lancaster, K.M.,Freed, J.H.,Hoffman, B.M.,Lin, H.,Ealick, S.E. (登録日: 2017-12-18, 公開日: 2018-04-11, 最終更新日: 2023-10-04)

• 主引用文献: Dong, M.,Kathiresan, V.,Fenwick, M.K.,Torelli, A.T.,Zhang, Y.,Caranto, J.D.,Dzikovski, B.,Sharma, A.,Lancaster, K.M.,Freed, J.H.,Ealick, S.E.,Hoffman, B.M.,Lin, H.; Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.; Science, 359:1247-1250, 2018; PubMed: 29590073; DOI: 10.1126/science.aao6595

実験手法

X-RAY DIFFRACTION (2.079 Å)