6BWU
Crystal structure of carboxyhemoglobin in complex with beta Cys93 modifying agent, TD3
Summary for 6BWU
Entry DOI | 10.2210/pdb6bwu/pdb |
Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, CARBON MONOXIDE, ... (6 entities in total) |
Functional Keywords | hemoglobin, antisickling, allosteric effector, td3, oxygen transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 32430.67 |
Authors | Musayev, F.N.,Safo, R.M.,Safo, M.K. (deposition date: 2017-12-15, release date: 2018-01-03, Last modification date: 2023-10-04) |
Primary citation | Nakagawa, A.,Ferrari, M.,Schleifer, G.,Cooper, M.K.,Liu, C.,Yu, B.,Berra, L.,Klings, E.S.,Safo, R.S.,Chen, Q.,Musayev, F.N.,Safo, M.K.,Abdulmalik, O.,Bloch, D.B.,Zapol, W.M. A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells. Mol. Pharm., 15:1954-1963, 2018 Cited by PubMed: 29634905DOI: 10.1021/acs.molpharmaceut.8b00108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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