6BWU

Crystal structure of carboxyhemoglobin in complex with beta Cys93 modifying agent, TD3

Summary for 6BWU

• Entry DOI: 10.2210/pdb6bwu/pdb
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, CARBON MONOXIDE, ... (6 entities in total)
• Functional Keywords: hemoglobin, antisickling, allosteric effector, td3, oxygen transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 32430.67

Authors

Musayev, F.N.,Safo, R.M.,Safo, M.K. (deposition date: 2017-12-15, release date: 2018-01-03, Last modification date: 2023-10-04)

• Primary citation: Nakagawa, A.,Ferrari, M.,Schleifer, G.,Cooper, M.K.,Liu, C.,Yu, B.,Berra, L.,Klings, E.S.,Safo, R.S.,Chen, Q.,Musayev, F.N.,Safo, M.K.,Abdulmalik, O.,Bloch, D.B.,Zapol, W.M.; A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.; Mol. Pharm., 15:1954-1963, 2018; PubMed: 29634905; DOI: 10.1021/acs.molpharmaceut.8b00108

Experimental method

X-RAY DIFFRACTION (2 Å)