6BWO

LarC2, the C-terminal domain of a cyclometallase involved in the synthesis of the NPN cofactor of lactate racemase, apo form

6BWO の概要

• エントリーDOI: 10.2210/pdb6bwo/pdb
• 分子名称: Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein (2 entities in total)
• 機能のキーワード: lar, nickel transferase, larc, hexamer, trimer, ctp, nickel, lactate, lactate racemization, lactate racemase, metal binding protein
• 由来する生物種: Lactobacillus plantarum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33638.29

構造登録者

Fellner, M.,Desguin, B.,Hausinger, R.P.,Hu, J. (登録日: 2017-12-15, 公開日: 2018-06-20, 最終更新日: 2024-04-03)

• 主引用文献: Desguin, B.,Fellner, M.,Riant, O.,Hu, J.,Hausinger, R.P.,Hols, P.,Soumillion, P.; Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.; J. Biol. Chem., 293:12303-12317, 2018; PubMed: 29887527; DOI: 10.1074/jbc.RA118.003741

実験手法

X-RAY DIFFRACTION (2.03 Å)