6BVF

Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the fluorescent allosteric modulator HAP-TAMRA

Summary for 6BVF

Entry DOI	10.2210/pdb6bvf/pdb
EMDB information	7294 7295
Descriptor	Capsid protein, Heteroaryldihydropyrimidine tetramethylrodamine (2 entities in total)
Functional Keywords	capsid, cpam, antiviral, fluorescent, virus like particle
Biological source	Hepatitis B virus genotype D subtype adw (isolate United Kingdom/adyw/1979)
Total number of polymer chains	4
Total formula weight	69043.27
Authors	Schlicksup, C.,Wang, J.C.,Zlotnick, A. (deposition date: 2017-12-12, release date: 2018-02-07, Last modification date: 2022-04-13)
Primary citation	Schlicksup, C.J.,Wang, J.C.,Francis, S.,Venkatakrishnan, B.,Turner, W.W.,VanNieuwenhze, M.,Zlotnick, A. Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids. Elife, 7:-, 2018 Cited by PubMed: 29377794 DOI: 10.7554/eLife.31473 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation