6BU6

Crystal Structure of the Human vaccinia-related kinase bound to a bis-difluorophenol-aminopyridine inhibitor

6BU6 の概要

• エントリーDOI: 10.2210/pdb6bu6/pdb
• 分子名称: Serine/threonine-protein kinase VRK1, 4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol), GLYCEROL, ... (6 entities in total)
• 機能のキーワード: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 166388.43

構造登録者

Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Santiago, A.S.,Azevedo, A.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (登録日: 2017-12-08, 公開日: 2017-12-20, 最終更新日: 2023-10-04)

• 主引用文献: Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Santiago, A.S.,Azevedo, H.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC); Crystal Structure of the Human vaccinia-related kinase bound to a bis-difluorophenol-aminopyridine inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)