6BQB

MGG4 Fab in complex with peptide

6BQB の概要

• エントリーDOI: 10.2210/pdb6bqb/pdb
• 分子名称: MGG4 Fab light chain, MGG4 Fab heavy chain, N-terminal junction peptide, ... (5 entities in total)
• 機能のキーワード: human fab fragment peptide binding plasmodium falciparum circumsporozoite protein, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49943.60

構造登録者

Oyen, D.,Tan, J.,Lanzavecchia, A.,Wilson, I.A. (登録日: 2017-11-27, 公開日: 2018-03-07, 最終更新日: 2018-04-25)

• 主引用文献: Tan, J.,Sack, B.K.,Oyen, D.,Zenklusen, I.,Piccoli, L.,Barbieri, S.,Foglierini, M.,Fregni, C.S.,Marcandalli, J.,Jongo, S.,Abdulla, S.,Perez, L.,Corradin, G.,Varani, L.,Sallusto, F.,Sim, B.K.L.,Hoffman, S.L.,Kappe, S.H.I.,Daubenberger, C.,Wilson, I.A.,Lanzavecchia, A.; A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.; Nat. Med., 24:401-407, 2018; PubMed: 29554084; DOI: 10.1038/nm.4513

実験手法

X-RAY DIFFRACTION (1.769 Å)