6BM4
Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP
Summary for 6BM4
Entry DOI | 10.2210/pdb6bm4/pdb |
Descriptor | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), ... (15 entities in total) |
Functional Keywords | complex, dna binding protein, dna-rna hybrid, transcription |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 12 |
Total formula weight | 482379.50 |
Authors | |
Primary citation | Wang, W.,Walmacq, C.,Chong, J.,Kashlev, M.,Wang, D. Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115:E2538-E2545, 2018 Cited by PubMed: 29487211DOI: 10.1073/pnas.1722050115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.951 Å) |
Structure validation
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