6BM4

Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP

6BM4 の概要

• エントリーDOI: 10.2210/pdb6bm4/pdb
• 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), ... (15 entities in total)
• 機能のキーワード: complex, dna binding protein, dna-rna hybrid, transcription
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 482379.50

構造登録者

Wang, W.,Wang, D. (登録日: 2017-11-13, 公開日: 2018-02-28, 最終更新日: 2024-03-13)

• 主引用文献: Wang, W.,Walmacq, C.,Chong, J.,Kashlev, M.,Wang, D.; Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.; Proc. Natl. Acad. Sci. U.S.A., 115:E2538-E2545, 2018; PubMed: 29487211; DOI: 10.1073/pnas.1722050115

実験手法

X-RAY DIFFRACTION (2.951 Å)