6BLP

Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP

Summary for 6BLP

• Entry DOI: 10.2210/pdb6blp/pdb
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), ... (16 entities in total)
• Functional Keywords: complex, dna binding protein, dna-rna hybrid, transcription
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 12
• Total formula weight: 482072.34

Authors

Wang, W.,Wang, D. (deposition date: 2017-11-11, release date: 2018-02-28, Last modification date: 2024-03-13)

• Primary citation: Wang, W.,Walmacq, C.,Chong, J.,Kashlev, M.,Wang, D.; Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.; Proc. Natl. Acad. Sci. U.S.A., 115:E2538-E2545, 2018; PubMed: 29487211; DOI: 10.1073/pnas.1722050115

Experimental method

X-RAY DIFFRACTION (3.203 Å)