6BLA

Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody

6BLA の概要

• エントリーDOI: 10.2210/pdb6bla/pdb
• 分子名称: AMM01 Fab Heavy chain, AMM01 Fab Light chain, 1,2-ETHANEDIOL, ... (9 entities in total)
• 機能のキーワード: ssgcid, structural genomics, seattle structural genomics center for infectious disease, antibody, fab, ebv, gh/gl, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49048.05

構造登録者

Pancera, M.,Weidle, C.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2017-11-09, 公開日: 2018-04-25, 最終更新日: 2019-11-13)

• 主引用文献: Snijder, J.,Ortego, M.S.,Weidle, C.,Stuart, A.B.,Gray, M.D.,McElrath, M.J.,Pancera, M.,Veesler, D.,McGuire, A.T.; An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.; Immunity, 48:799-811.e9, 2018; PubMed: 29669253; DOI: 10.1016/j.immuni.2018.03.026

実験手法

X-RAY DIFFRACTION (1.55 Å)