6BHZ
Trastuzumab Fab D185A (Light Chain) Mutant.
Summary for 6BHZ
Entry DOI | 10.2210/pdb6bhz/pdb |
Descriptor | Trastuzumab Anti-HER2 Fab Heavy Chain, Trastuzumab Anti-HER2 Fab Light Chain D185A, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | fab, immunoglobulin, mutant, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 95070.01 |
Authors | DiDonato, M.,Spraggon, G. (deposition date: 2017-10-31, release date: 2018-02-14, Last modification date: 2023-10-04) |
Primary citation | Pham, G.H.,Ou, W.,Bursulaya, B.,DiDonato, M.,Herath, A.,Jin, Y.,Hao, X.,Loren, J.,Spraggon, G.,Brock, A.,Uno, T.,Geierstanger, B.H.,Cellitti, S.E. Tuning a Protein-Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation. Chembiochem, 19:799-804, 2018 Cited by PubMed: 29388367DOI: 10.1002/cbic.201700611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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