6BHI
Crystal structure of SETDB1 with a modified H3 peptide
Summary for 6BHI
Entry DOI | 10.2210/pdb6bhi/pdb |
Descriptor | Histone-lysine N-methyltransferase SETDB1, Histone H3.1, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics, epigenetics, histone modification, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q15047 P68431 |
Total number of polymer chains | 2 |
Total formula weight | 29386.75 |
Authors | Qin, S.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2017-10-30, release date: 2017-12-06, Last modification date: 2023-11-15) |
Primary citation | Jurkowska, R.Z.,Qin, S.,Kungulovski, G.,Tempel, W.,Liu, Y.,Bashtrykov, P.,Stiefelmaier, J.,Jurkowski, T.P.,Kudithipudi, S.,Weirich, S.,Tamas, R.,Wu, H.,Dombrovski, L.,Loppnau, P.,Reinhardt, R.,Min, J.,Jeltsch, A. H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8:2057-2057, 2017 Cited by PubMed: 29234025DOI: 10.1038/s41467-017-02259-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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