6BE3
Crystal structure of a polysaccharide-binding human Fab (F598) in complex with N-acetyl-D-glucosamine (GlcNAc)
Summary for 6BE3
| Entry DOI | 10.2210/pdb6be3/pdb |
| Related | 6BE2 6BE4 |
| Descriptor | Fab (F598) Heavy Chain, Fab (F598) Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | immunoglobulin, human antibody, antigen binding fragment, n-acetyl-d-glucosamine, complex, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 2 |
| Total formula weight | 47518.73 |
| Authors | Soliman, C.,Ramsland, P.A. (deposition date: 2017-10-24, release date: 2018-02-21, Last modification date: 2023-10-04) |
| Primary citation | Soliman, C.,Walduck, A.K.,Yuriev, E.,Richards, J.S.,Cywes-Bentley, C.,Pier, G.B.,Ramsland, P.A. Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine. J. Biol. Chem., 293:5079-5089, 2018 Cited by PubMed: 29449370DOI: 10.1074/jbc.RA117.001170 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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