6BDQ

Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000074 (Compound 10a) Complex

Summary for 6BDQ

• Entry DOI: 10.2210/pdb6bdq/pdb
• Descriptor: Sulfotransferase oxamniquine resistance protein, ADENOSINE-3'-5'-DIPHOSPHATE, (2-nitro-4-{[(3S)-piperidin-3-yl]amino}phenyl)methanol, ... (4 entities in total)
• Functional Keywords: sulfotransferase, parasite, drug resistance, transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 30671.05

Authors

Taylor, A.B. (deposition date: 2017-10-24, release date: 2018-10-03, Last modification date: 2023-10-04)

• Primary citation: Rugel, A.,Tarpley, R.S.,Lopez, A.,Menard, T.,Guzman, M.A.,Taylor, A.B.,Cao, X.,Kovalskyy, D.,Chevalier, F.D.,Anderson, T.J.C.,Hart, P.J.,LoVerde, P.T.,McHardy, S.F.; Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.; ACS Med Chem Lett, 9:967-973, 2018; PubMed: 30344901; DOI: 10.1021/acsmedchemlett.8b00257

Experimental method

X-RAY DIFFRACTION (1.83 Å)