6BCS

LilrB2 D1D2 domains complexed with benzamidine

Summary for 6BCS

• Entry DOI: 10.2210/pdb6bcs/pdb
• Descriptor: Leukocyte immunoglobulin-like receptor subfamily B member 2, BENZAMIDINE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: receptor, ig like domains, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 22773.67

Authors

Cao, Q.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2017-10-20, release date: 2018-09-05, Last modification date: 2023-10-04)

• Primary citation: Cao, Q.,Shin, W.S.,Chan, H.,Vuong, C.K.,Dubois, B.,Li, B.,Murray, K.A.,Sawaya, M.R.,Feigon, J.,Black, D.L.,Eisenberg, D.S.,Jiang, L.; Inhibiting amyloid-beta cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.; Nat Chem, 10:1213-1221, 2018; PubMed: 30297750; DOI: 10.1038/s41557-018-0147-z

Experimental method

X-RAY DIFFRACTION (2.1 Å)