6BCS

LilrB2 D1D2 domains complexed with benzamidine

6BCS の概要

• エントリーDOI: 10.2210/pdb6bcs/pdb
• 分子名称: Leukocyte immunoglobulin-like receptor subfamily B member 2, BENZAMIDINE, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: receptor, ig like domains, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22773.67

構造登録者

Cao, Q.,Sawaya, M.R.,Eisenberg, D.S. (登録日: 2017-10-20, 公開日: 2018-09-05, 最終更新日: 2023-10-04)

• 主引用文献: Cao, Q.,Shin, W.S.,Chan, H.,Vuong, C.K.,Dubois, B.,Li, B.,Murray, K.A.,Sawaya, M.R.,Feigon, J.,Black, D.L.,Eisenberg, D.S.,Jiang, L.; Inhibiting amyloid-beta cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.; Nat Chem, 10:1213-1221, 2018; PubMed: 30297750; DOI: 10.1038/s41557-018-0147-z

実験手法

X-RAY DIFFRACTION (2.1 Å)