6BBX
Crystal structure of TnmS3 in complex with TNM C
Summary for 6BBX
Entry DOI | 10.2210/pdb6bbx/pdb |
Descriptor | Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate (3 entities in total) |
Functional Keywords | glyoxalase/bleomycin resistance protein/dioxygenase superfamily, structural genomics, midwest center for structural genomics, mcsg, lyase, tiancimycin-binding protein |
Biological source | Streptomyces sp. CB03234 |
Total number of polymer chains | 2 |
Total formula weight | 32149.61 |
Authors | Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) (deposition date: 2017-10-19, release date: 2018-07-04, Last modification date: 2023-10-04) |
Primary citation | Chang, C.Y.,Yan, X.,Crnovcic, I.,Annaval, T.,Chang, C.,Nocek, B.,Rudolf, J.D.,Yang, D.,Babnigg, G.,Joachimiak, A.,Phillips Jr., G.N.,Shen, B. Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25:1075-1085.e4, 2018 Cited by PubMed: 29937405DOI: 10.1016/j.chembiol.2018.05.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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