6B72
A novel HIV-1 Nef dimer interface induced by a single octyl-glucoside molecule
Summary for 6B72
| Entry DOI | 10.2210/pdb6b72/pdb |
| Descriptor | Protein Nef, octyl beta-D-glucopyranoside (2 entities in total) |
| Functional Keywords | hiv-1 nef, dimer, viral protein |
| Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) |
| Total number of polymer chains | 6 |
| Total formula weight | 107461.48 |
| Authors | Wu, M.,Augelli-Szafran, C.E.,Ptak, R.G.,Smithgall, T.E. (deposition date: 2017-10-03, release date: 2018-02-21, Last modification date: 2024-03-13) |
| Primary citation | Wu, M.,Alvarado, J.J.,Augelli-Szafran, C.E.,Ptak, R.G.,Smithgall, T.E. A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding. PLoS ONE, 13:e0192512-e0192512, 2018 Cited by PubMed: 29415006DOI: 10.1371/journal.pone.0192512 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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