6AZP

A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN)

6AZP の概要

• エントリーDOI: 10.2210/pdb6azp/pdb
• 分子名称: Myeloperoxidase, Staphylococcal Peroxidase Inhibitor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: myeloperoxidase, inhibitor, complex, innate immune evasion, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73849.08

構造登録者

Ramyar, K.X.,Geisbrecht, B.V. (登録日: 2017-09-11, 公開日: 2017-12-27, 最終更新日: 2023-11-15)

• 主引用文献: de Jong, N.W.M.,Ploscariu, N.T.,Ramyar, K.X.,Garcia, B.L.,Herrera, A.I.,Prakash, O.,Katz, B.B.,Leidal, K.G.,Nauseef, W.M.,van Kessel, K.P.M.,van Strijp, J.A.G.,Geisbrecht, B.V.; A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN).; J. Biol. Chem., 293:2260-2271, 2018; PubMed: 29306874; DOI: 10.1074/jbc.RA117.000134

実験手法

X-RAY DIFFRACTION (2.291 Å)