6AYQ
Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A
Summary for 6AYQ
Entry DOI | 10.2210/pdb6ayq/pdb |
Descriptor | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, GLYCEROL, ... (4 entities in total) |
Functional Keywords | mtan enzyme, foodborne diseases, hydrolase, transferase |
Biological source | Campylobacter jejuni |
Total number of polymer chains | 2 |
Total formula weight | 53303.72 |
Authors | Cameron, S.A.,Harijan, R.K.,Ducati, R.G.,Bonanno, J.B.,Almo, S.C.,Schramm, V.L. (deposition date: 2017-09-08, release date: 2018-09-12, Last modification date: 2023-10-04) |
Primary citation | Ducati, R.G.,Harijan, R.K.,Cameron, S.A.,Tyler, P.C.,Evans, G.B.,Schramm, V.L. Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase. ACS Chem. Biol., 13:3173-3183, 2018 Cited by PubMed: 30339406DOI: 10.1021/acschembio.8b00781 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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