6AXU

W203Y Epi-isozizaene synthase

Summary for 6AXU

Entry DOI	10.2210/pdb6axu/pdb
Descriptor	Epi-isozizaene synthase, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE 2-, ... (5 entities in total)
Functional Keywords	terpenoid cyclase, lyase
Biological source	Streptomyces coelicolor
Total number of polymer chains	1
Total formula weight	44134.17
Authors	Blank, P.N.,Barrow, G.H.,Christianson, D.W. (deposition date: 2017-09-07, release date: 2017-10-18, Last modification date: 2023-10-04)
Primary citation	Blank, P.N.,Barrow, G.H.,Chou, W.K.W.,Duan, L.,Cane, D.E.,Christianson, D.W. Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes. Biochemistry, 56:5798-5811, 2017 Cited by PubMed: 28967743 DOI: 10.1021/acs.biochem.7b00895 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.822 Å)

Structure validation